GLUTATHIONE REDUCES FEMALE INFERTILITY

Positive Effects on Fertility, Conception and Pregnancy

Female infertility has become an increasing problem among women of childbearing years. Recent statistics show that more women are becoming pregnant past the age of 30, greatly reducing family size. Women over the age of 30 also run the risk of failed attempts at successful pregnancy, mainly due to miscarriages caused by cellular damage caused by free radicals. Giving birth at an older age increases the potential for birth defects and developmental delays in an infant.

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GLUTATHIONE AND AGING

Aging is a part of life, but healthy aging requires optimal glutathione levels. Glutathione synthesis decreases significantly as we age: teenagers have the highest levels, while those over age 60 have the lowest. Interestingly, the elderly (and in particular those 100 and over) who are in the best health have the highest levels of glutathione, on par with young adults.

"With normal aging, total glutathione levels decrease, but the centenarians in this study showed levels similar to those of young adults."

GLUTATHIONE AND DENTAL HEALTH

As the master antioxidant, Glutathione is the most important redox regulator that controls inflammatory processes, including the inflammation that occurs in the mouth and around the teeth (the periodontium). Patients with periodontitis (gum infection) have lower antioxidant and reduced glutathione status. Proper oral hygiene is certainly important, but so too is supporting the internal glutathione system. The implications of dental health and its connection with a variety of conditions is far-reaching.

GLUTATHIONE AND INFLAMMATION

Oxidative stress and chronic inflammation go hand in hand. It is important to provide cells with the building blocks necessary for the adequate production of Glutathione.

- "Acute" (short term) inflammation is the body's protective reaction to things like infections, radiation, harmful chemicals, foreign particles, trauma, and stress. Acute inflammation is also involved in tissue repair.

- Inflammation that fails to regulate is called "chronic" (long term) inflammation and contributes to the development and progression of numerous diseases and conditions. Limiting chronic inflammation is essential.

- "Redox homeostasis" is a kind of molecular balance inside the cell between Reactive Oxygen Species (ROS) and antioxidants, with the master antioxidant Glutathione (GSH) playing a major role. Oxidative stress occurs when ROS become excessive and outnumber available antioxidant resources.

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ALZHEIMER'S DISEASE AND GLUTATHIONE

"Roughly twenty years before the first symptoms of Alzheimer’s disease appear, inflammatory changes in the brain can be seen, according to a new study. The findings of the researchers, who monitored several pathological changes in the brain, suggest that activation of astrocytes at an early stage can greatly influence the development of the disease."

What's the connection? Research already has shown that glutathione levels are decreased in Alzheimer's patients. Astrocytes are a type of brain cell that rely on glutathione to maintain healthy brain function; in fact, astrocytes "shuttle" glutathione to neurons, which suggests that neurons depend on astrocytes for antioxidant defense. This new research shows that astrocyte-related